Consultations in London & Manchester | Treatment in Izmir, Turkey | Caring for UK patients since 2005
Also called: menopause, perimenopause, hot flushes, hot flashes, night sweats, mood swings hormones, going through the change, hormone replacement, hormone therapy
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Menopause symptoms are primarily caused by changes in ovarian function and fluctuating levels of hormones, particularly oestrogen and progesterone. Before menopause, during the stage known as perimenopause, hormone levels can rise and fall unpredictably. This can cause periods to become irregular, heavier, lighter, longer or shorter. Changes in oestrogen also affect the brain’s regulation of body temperature, contributing to characteristic vasomotor symptoms such as hot flushes and night sweats. These hormonal fluctuations can begin several years before the final menstrual period.
Oestrogen influences many tissues beyond the reproductive system, which is why menopause symptoms can be wide-ranging. Changes may affect sleep, mood, concentration, skin, hair, joints, muscles, the urinary tract and genital tissues. Vaginal dryness, irritation, discomfort during sex, reduced sexual desire and urinary symptoms can develop as oestrogen levels decline. Some people experience headaches, palpitations, anxiety, low mood or problems with memory and concentration. Sleep disruption caused by night sweats can further contribute to tiredness, irritability and difficulty concentrating. Symptoms and their severity vary considerably, and some people experience very few difficulties.
Menopause most commonly occurs naturally with age, but symptoms can develop earlier when ovarian function declines prematurely or following certain medical treatments. Surgical removal of both ovaries can cause an abrupt menopause, while chemotherapy, radiotherapy and some medications can affect ovarian function. Longer-term reductions in oestrogen are also relevant to bone and cardiovascular health, although individual risk depends on many factors. Importantly, symptoms occurring around menopausal age should not automatically be attributed to menopause: thyroid disorders, anaemia, medication effects and other health conditions can produce similar symptoms and may require separate investigation.
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Treatments that address this
Professional advice is worthwhile when menopause symptoms interfere with sleep, work, relationships, sexual health, emotional wellbeing or everyday activities. There is no requirement to wait until periods have completely stopped before discussing symptoms, as support can be appropriate during perimenopause.
It is particularly important to seek medical advice if menopause-like symptoms occur before the age of 45, and especially before 40, as earlier loss of ovarian function may require further assessment. New or unexplained symptoms should also be evaluated rather than automatically attributed to menopause.
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